Iguratimod as an alternative induction therapy for refractory lupus nephritis: a preliminary investigational study
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چکیده
منابع مشابه
Rituximab alone as induction therapy for membranous lupus nephritis
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Despite the significant advances in the field, up to one-third of lupus nephritis (LN) patients still do not respond adequately to initial immunosuppressive treatment. This group of patients is heterogeneous in terms of clinical presentation (deterioration of glomerular filtration rate, variable degrees of persistent proteinuria, active urine sediment) and the potential for reversion (ongoing k...
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BACKGROUND Maintenance therapy, often with azathioprine or mycophenolate mofetil, is required to consolidate remission and prevent relapse after the initial control of lupus nephritis. METHODS We carried out a 36-month, randomized, double-blind, double-dummy, phase 3 study comparing oral mycophenolate mofetil (2 g per day) and oral azathioprine (2 mg per kilogram of body weight per day), plus...
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INTRODUCTION While the role of mycophenolate mofetil (MMF) in the management of lupus nephritis has been increasingly recognized, limited information is available regarding its efficacy and safety as a long-term maintenance treatment. The aim of the present study was to evaluate the efficacy and safety profile of MMF as maintenance therapy for proliferative lupus nephritis. METHODS Thirty-thr...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2020
ISSN: 1478-6362
DOI: 10.1186/s13075-020-02154-7